In the past, she hacked every security system, including the FBI. When she was captured, she was instead recruited for the FBI. She was also previously involved on a case with Gat and Matt Miller regarding Persephone Brimstone's surrender.
She is one of the four characters from Saints Row series that are playable, others being Kingpin, Yeti, and Gat.
She is also the only female Saints Row character that is playable as well.
Safeword and Lazarus are the only two agents that weren't featured or advertised in any trailers prior to the release of Agents of Mayhem.
While not in the player's squad, Safeword can be found under the table on her laptop at the ARK's lounge (immediately behind the spawn area). This is a reference to the Phone Phreak cutscene in Saints Row: The Third, where The Protagonist finds her under the table at Smiling Jack's.
She is mention in a conversation between Gat and Rama.
Her signature vehicle is the Mockingbird, complete with her own unique skin.
Its license plate, T-CUP, is a reference to Kinzie's line, "Mine's Teacup", as well as the source of her codename in her debut mission in Saints Row: The Third.
One of Safeword's idle animations shows her drink from a can, if you look close, you can see that it's actually a can of Saints Flow, with the M.A.Y.H.E.M. Saints logo, replacing the original logo. Saints Flow is the Saints branded energy drink from Saints Row: The Third and Saints Row IV.